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Mechanism of Modified Erxian Decoction Regulating Perimenopausal Syndrome via SIRT1/Kisspeptin/GnRH Signaling Pathway
Updated：2025-10-16
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    • Mechanism of Modified Erxian Decoction Regulating Perimenopausal Syndrome via SIRT1/Kisspeptin/GnRH Signaling Pathway

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    • “The latest research has found that Jiawei Erxian Tang can multi-target regulate the HPG axis function in perimenopausal syndrome rats, upregulate SIRT1 expression, inhibit excessive activation of the Kisspeptin/GnRH signaling pathway, restore the balance of gonadotropin secretion, and increase estrogen levels.”
    • HUANG Ruiyu , LEI Fang , LIU Wuchaonan , YANG Jingjing , ZENG Qianru , LUO Shengping , CHEN Yanling , ZHANG Mengge , SHEN Fanshun , DENG Yihui , LI Dingxiang
    • Chinese Journal of Experimental Traditional Medical Formulae Vol. 31, Issue 22, Pages: 51-62(2025)

    • DOI： 10.13422/j.cnki.syfjx.20251101     

      CLC：

    • Revised：2025-06-10 ，

      Accepted：10 June 2025 ，

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Related Author

LI Dingxiang
HUANG Ruiyu
SHEN Fanshun
DENG Yihui
LIANG Haiyan
MA Kun
MA Xiaona
HU Shiwan

Related Institution

Hunan Chunguang Jiuhui Modern Chinese Medicine Co. Ltd，Liuyang
Institute of Metabolic Diseases，Guang'anmen Hospital，China Academy of Chinese Medical Sciences
Japan Friendship Hospital
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Beijing University of Chinese Medicine Third Affiliated Hospital