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Xianlian Jiedu Prescription Suppresses Colorectal Cancer EMT by Blocking Tumor-associated Macrophage-derived CCL5 Secretion and Inhibiting STAT3/β-catenin Signaling Pathway
Updated：2025-09-08
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    • Xianlian Jiedu Prescription Suppresses Colorectal Cancer EMT by Blocking Tumor-associated Macrophage-derived CCL5 Secretion and Inhibiting STAT3/β-catenin Signaling Pathway

    • “The latest research has found that Xianlian Jiedu Formula can effectively inhibit the metastasis of colorectal cancer, and its mechanism may involve targeting CCL5 derived from tumor associated macrophages and inhibiting the imbalance of EMT marker expression mediated by STAT3 phosphorylation.”
    • QIAN Jingyang , TAO Lihuiping , ZHANG Qinchang , SHEN Weixing , LI Liu , SUN Dongdong , CHENG Haibo
    • Chinese Journal of Experimental Traditional Medical Formulae Vol. 31, Issue 19, Pages: 138-147(2025)

    • DOI： 10.13422/j.cnki.syfjx.20251324     

      CLC：

    • Revised：2025-05-16 ，

      Accepted：29 May 2025 ，

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