Your Location：
Home >
Browse articles >
Impact and Mechanism of Gypenosides on MAFLD Mice via Regulating SIRT6/CREB/Nur77 Signaling Pathway and Mediating Apoptosis
Updated：2026-07-01
Previous|Next

    • Impact and Mechanism of Gypenosides on MAFLD Mice via Regulating SIRT6/CREB/Nur77 Signaling Pathway and Mediating Apoptosis

      Enhanced Publication
    • “Gynostemma pentaphyllum saponins can improve lipid deposition in the liver of MAFLD mice, which is related to regulating the SIRT6/CREB/Nur77 signaling pathway and affecting cell apoptosis. The research team validated this mechanism through network pharmacology and animal experiments, providing a new target for the treatment of metabolic related fatty liver disease.”
    • SUN Xiaofei , SONG Nan , CAO Yuan , LIU Yu , ZHANG Meiling , ZHU Jingxuan , WANG Jiaxin , DONG Yuanguang , JIA Lianqun
    • Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 15, Pages: 35-44(2026)

    • DOI： 10.13422/j.cnki.syfjx.20251613     

      CLC：

    • Revised：2025-11-04 ，

      Accepted：11 November 2025 ，

    Scan QR Code

  •  
  •  

  • AI Introduction

  • Full Text(HTML)

  • Figs( 5 ) Tabs( 8 )

  • References

  • Publication Info

  • Metrics

165

Views

116

Downloads

0

CSCD

Alert me when the article has been cited
Submit
Tools
  • BibTeXDownload
  • EndnoteDownload
  • RefMan Download
  • NoteExpressDownload
  • NoteFirstDownload

Related Articles

Traditional Chinese Medicine Intervenes in Endoplasmic Reticulum Stress to Treat Diabetic Microvascular Complications：A Review
Hezhong Xiaopi Granules Regulate Ncln-CHOP Axis to Inhibit Endoplasmic Reticulum Stress and Reduce Gastric Mucosal Cell Apoptosis
Xiao Chaihutang Combined with Erchen Tang Ameliorates Metabolic-associated Fatty Liver Disease in Mice by Regulating SIRT1/PGC-1α/PPARα Signaling Pathway
Modified Guizhi Fulingwan Regulates miR-34a-5p/DLL1/Notch Signaling Pathway to Promote Apoptosis and Inhibit Prostate Cancer
Traditional Chinese Medicine Intervention in Parkinson's Disease Based on Keap1/Nrf2/ARE Signaling Pathway： A Review

Related Author

ZHOU Zhenlong
DUAN Yu
PANG Yutian
JIA Ying
LI Mingwei
SHA Hongyu
ZHOU Haichun
LI Hongzheng

Related Institution

The Second Clinical Medical College， Heilongjiang University of Chinese Medicine
Shandong University of Traditional Chinese Medicine
Fudan University Shanghai Cancer Center
Shanghai Haijiang Geriatric Hospital
The Fourth Affiliated Hospital of Heilongjiang University of Chinese Medicine