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Polygonati Rhizoma Polysaccharides Improve Cognitive and Emotional Functions of Ovariectomy-AD Model Rats Through Modulating ERα/PI3K/Akt Pathway
Updated:2026-04-01
    • Polygonati Rhizoma Polysaccharides Improve Cognitive and Emotional Functions of Ovariectomy-AD Model Rats Through Modulating ERα/PI3K/Akt Pathway

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    • “Expert research has found that Polygonatum sibiricum polysaccharides can improve cognitive and emotional function in ovariectomized Alzheimer's disease model rats, and its mechanism is related to regulating the estrogen receptor alpha/phosphatidylinositol 3-kinase/protein kinase B signaling pathway and inhibiting neuroinflammation, oxidative stress, and cell apoptosis.”
    • ZHANG Gengchao , YANG Li , ZHANG Yuan , ZHOU Tao
    • Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 9, Pages: 154-162(2026)
    • DOI: 10.13422/j.cnki.syfjx.20251802     

      CLC:
    • Revised:2025-12-09 ,

      Accepted:11 December 2025 ,

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