Tongnao Decoction Promotes Angiogenesis and Alleviates Cerebral Ischemic Injury via PI3K/Akt/GSK-3β Signaling Pathway

LIU Yan; WU Yang; PENG Wanhui; CHEN Jingyi; GAN Jiale; LI Li; XIA Yangjingyi; LI Yunze; CHEN Zhaoyao; LI Wenlei; WU Minghua

doi:10.13422/j.cnki.syfjx.20251937

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Tongnao Decoction Promotes Angiogenesis and Alleviates Cerebral Ischemic Injury via PI3K/Akt/GSK-3

β

Signaling Pathway

Updated：2026-04-01

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- Tongnao Decoction Promotes Angiogenesis and Alleviates Cerebral Ischemic Injury via PI3K/Akt/GSK-3 $β$ Signaling Pathway
- “The mechanism of action of Tongnaoyin on mice with acute ischemic stroke was studied. Experts established a mouse model of cerebral ischemic injury and found that Tongnaoyin can regulate the PI3K/Akt/GSK-3 β signaling pathway, promote angiogenesis, and improve cerebral ischemic injury.”
- LIU Yan , WU Yang , PENG Wanhui , CHEN Jingyi , GAN Jiale , LI Li , XIA Yangjingyi , LI Yunze , CHEN Zhaoyao , LI Wenlei , WU Minghua
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 9, Pages: 100-110(2026)
- Affiliations：
  1.The Affiliated Hospital of Nanjing University of Chinese Medicine/Jiangsu Province Hospital of Chinese Medicine/The First School of Clinical Medicine of Nanjing University of Chinese Medicine， Nanjing 210029，China
  2.Nanjing Jiangbei Hospital，Nanjing 210044，China
- Author bio：
- Funds：
- DOI： 10.13422/j.cnki.syfjx.20251937
  CLC：
- Revised：2025-09-18 ，
  Accepted：18 September 2025 ，
- Accepted：
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Tongnao Decoction Promotes Angiogenesis and Alleviates Cerebral Ischemic Injury via PI3K/Akt/GSK-3

β

Signaling Pathway

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Tongnao Decoction Promotes Angiogenesis and Alleviates Cerebral Ischemic Injury via PI3K/Akt/GSK-3 $β$ Signaling Pathway

DOI： 10.13422/j.cnki.syfjx.20251937

AI Introduction

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Figs( 7 ) Tabs( 5 )

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