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Mechanisms of Sargentodoxae Caulis in Alleviating Neuropathic Pain via Regulation of BDNF/TrkB/CaMKⅡ/CREB Signaling Pathway
Updated：2026-05-15
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    • Mechanisms of Sargentodoxae Caulis in Alleviating Neuropathic Pain via Regulation of BDNF/TrkB/CaMKⅡ/CREB Signaling Pathway

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    • “Introduced a new discovery on the analgesic mechanism of Tripterygium wilfordii, and the team validated that Tripterygium wilfordii inhibits neuronal excitability and central sensitization by downregulating the BDNF/TrkB/CaMKII/CREB signaling pathway to alleviate neuropathic pain, providing a solution for NP treatment”
    • WANG Fangfang , HU Qiqi , LIANG Dayi , WU Jing , WANG Long , TANG Ting , CHEN Peng
    • Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 12, Pages: 102-110(2026)

    • DOI： 10.13422/j.cnki.syfjx.20251939     

      CLC：

    • Revised：2025-09-22 ，

      Accepted：24 September 2025 ，

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