Mechanism of Shaoyaotang in Ameliorating Colitis-associated Carcinogenesis in Mice via Modulating AMPK/NF-κB/HIF-1α Signaling Pathway

CHEN Xue; WANG Chenglei; WU Ying; YANG Bingwei; ZHAI Haoyu; LI Weidong

doi:10.13422/j.cnki.syfjx.20252026

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Mechanism of Shaoyaotang in Ameliorating Colitis-associated Carcinogenesis in Mice via Modulating AMPK/NF-κB/HIF-1α Signaling Pathway

Updated：2026-07-16

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- Mechanism of Shaoyaotang in Ameliorating Colitis-associated Carcinogenesis in Mice via Modulating AMPK/NF-κB/HIF-1α Signaling Pathway
- “Shao Yao Tang can improve colitis and tumor formation in CAC mice, and its mechanism is related to regulating the AMPK/NF - κ B/HIF-1 α signaling pathway. Researchers have verified this hypothesis through in vitro and in vivo experiments, providing a new treatment plan for colitis related colorectal cancer.”
- CHEN Xue , WANG Chenglei , WU Ying , YANG Bingwei , ZHAI Haoyu , LI Weidong
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 16, Pages: 1-10(2026)
- Affiliations：
  1.Guang'anmen Hospital， China Academy of Chinese Medical Sciences， Beijing 100053，China
  2.Hospital of Chengdu University of Traditional Chinese Medicine， Chengdu 610072，China
  3.Shaanxi University of Chinese Medicine， Xianyang 712000，China
- Author bio：
- Funds：
- DOI： 10.13422/j.cnki.syfjx.20252026
  CLC：
- Revised：2025-09-15 ，
  Accepted：23 September 2025 ，
- Accepted：
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Mechanism of Shaoyaotang in Ameliorating Colitis-associated Carcinogenesis in Mice via Modulating AMPK/NF-κB/HIF-1α Signaling Pathway

DOI： 10.13422/j.cnki.syfjx.20252026

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