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Zhuluan Decoction Ameliorates Premature Ovarian Insufficiency by Inhibiting Excessive Autophagy of KGN Through Regulation of PI3K/Akt/mTOR Pathway
Updated:2026-03-19
    • Zhuluan Decoction Ameliorates Premature Ovarian Insufficiency by Inhibiting Excessive Autophagy of KGN Through Regulation of PI3K/Akt/mTOR Pathway

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    • “Based on the PI3K/Akt/mTOR signaling pathway, experts explored the mechanism of action of Zhuyun Tang on early-onset ovarian insufficiency (POI), and verified its inhibitory effect on excessive autophagy and improvement of POI through cell experiments, providing new ideas for related treatments.”
    • CHEN Yao , TIAN Sainan , ZENG Jing , YI Xingxing , LIU Wen'e , LEI Lei , TANG Li
    • Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 8, Pages: 89-98(2026)
    • DOI: 10.13422/j.cnki.syfjx.20252306     

      CLC:
    • Revised:2025-10-15 ,

      Accepted:27 October 2025 ,

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Related Author

CHEN Yao
TIAN Sainan
ZENG Jing
YI Xingxing
LIU Wen'e
LEI Lei
TANG Li
CHEN Yao

Related Institution

The First Affiliated Hospital of Hunan University of Chinese Medicine
School of Integrated Chinese and Western Medicine, Hunan University of Chinese Medicine
School of Traditional Chinese Medicine, Hunan University of Chinese Medicine
College of Integrated Traditional Chinese and Western Medicine, Hunan University of Chinese Medicine
College of Traditional Chinese Medicine(TCM),Ningxia Medical University