“Epimedium, as a traditional Chinese medicine for tonifying kidney and strengthening yang, can play a key role in the treatment of male diseases through multi-component synergy, multi-target regulation, and multi-channel intervention. This article introduces its research progress in the field of male diseases, and explores the mechanism of action of active ingredients of Epimedium in the treatment of erectile dysfunction, male infertility, prostate cancer, and other diseases, providing a solution for the development of innovative traditional Chinese medicine preparations for male diseases.”