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Banxia Xiexintang Affect PD-L1 Expression Induced by Gastric Cancer Cell-derived Exosomes in Bone Marrow Mesenchymal Stem Cells via Akt/c-Myc Signaling Axis
Updated：2026-09-17
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    • Banxia Xiexintang Affect PD-L1 Expression Induced by Gastric Cancer Cell-derived Exosomes in Bone Marrow Mesenchymal Stem Cells via Akt/c-Myc Signaling Axis

    • “Banxia Xiexin Tang can reduce the expression of PD-L1 induced by extracellular vesicles in BMSCs of gastric cancer cells and inhibit cell migration by regulating the Akt/c-Myc signaling axis. It has a synergistic effect with PD-L1 monotherapy, opening up a new direction for research on gastric cancer treatment.”
    • ZHANG Wei , LIU Xiping , SHI Lijuan , ZHU Zhongbo , WANG Qingmiao
    • Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 20, Pages: 94-101(2026)

    • DOI： 10.13422/j.cnki.syfjx.20260225     

      CLC：

    • Revised：2025-12-26 ，

      Accepted：31 December 2025 ，

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Related Author

ZHU Zhongbo
YANG Wenying
WEI Jingjing
LI Fangni
SHI Lijuan
LIU Xiping
LIU Xiping
YANG Wenying

Related Institution

Gansu Provincial Key Laboratory of Exploration and Innovation Transformation of Chinese Medicine Prescriptions， Engineering Laboratory for New Traditional Chinese Medicine Product Development of Gansu Province， Gansu University of Chinese Medicine
Affiliated Hospital of Gansu University of Chinese Medicine
Gansu Provincial Key Laboratory of Exploration and Innovation Transformation of Chinese Medicine Prescriptions， Engineering Laboratory for New Traditional Chinese Medicine Product Development of Gansu Province， Gansu University of Chinese Medicine
The First Clinical Medical College of Shandong University of Traditional Chinese Medicine
Institute of Chinese Medical Literature and Culture， Shandong University of Traditional Chinese Medicine