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Effect Difference and Mechanisms of Zishenwan Against Chronic Prostatitis Before and After Salt-processing of Anemarrhenae Rhizoma and Phellodendri Chinensis Cortex by Integrating Network Pharmacology and Metabolomics
Updated：2026-05-29
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    • Effect Difference and Mechanisms of Zishenwan Against Chronic Prostatitis Before and After Salt-processing of Anemarrhenae Rhizoma and Phellodendri Chinensis Cortex by Integrating Network Pharmacology and Metabolomics

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    • “The research team has revealed the mechanism of action of salt roasted Zishen Wan in treating chronic prostatitis. "After salt roasting, the content of berberine, berberine and other components in Zishen Wan increases, which may enhance the therapeutic effect on CP by inhibiting signaling pathways such as PI3K/Akt and MAPK, as well as multi-target regulation of metabolic pathways such as tryptophan, arginine and pantothenic acid." This provides new evidence for the study of enhancing the efficacy of traditional Chinese medicine processing.”
    • ZHAO Shangling , MENG Xiao , LI Sirui , TAN Rui , HU Changjiang , YU Lingying , CHEN Zhimin
    • Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 13, Pages: 177-187(2026)

    • DOI： 10.13422/j.cnki.syfjx.20260268     

      CLC：

    • Revised：2026-03-08 ，

      Accepted：18 March 2026 ，

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