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Effect of Zhengan Xifengtang on Intestinal Mucosal Barrier in Spontaneously Hypertensive Rats via FXR-MLCK/p-MLC Pathway
Updated:2026-09-11
    • Effect of Zhengan Xifengtang on Intestinal Mucosal Barrier in Spontaneously Hypertensive Rats via FXR-MLCK/p-MLC Pathway

    • Zhengan Xifeng Tang may regulate the FXR-MLCK/p-MLC signaling pathway, enhance the expression of tight junction proteins, thereby reducing intestinal mucosal permeability, promoting mucosal barrier repair, reducing LPS release into the bloodstream, and thus lowering blood pressure levels, providing a new solution for the treatment of hypertensive intestinal barrier injury.
    • SI Meilong , JIN Hua , WANG Yu , ZHANG Qiuju , LIU Tao , YONG Yun , BAO Xuan
    • Chinese Journal of Experimental Traditional Medical Formulae Pages: 1-10(2026)
    • DOI: 10.13422/j.cnki.syfjx.20260306     

      CLC:
    • Revised:2026-03-05

      Accepted:09 March 2026

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Related Author

LING Bishi
JIN Hua
QI Shangwen
LIU Shuangfang
SI Meilong
LIU Zhijun
LIU Shuangfang
JIN Hua

Related Institution

Affiliated Hospital of Gansu University of Chinese Medicine
Shenzhen Luohu People 's Hospital
Gansu University of Chinese Medicine,Key Laboratory of Dunhuang Medicine and Transformation Ministry of Education
Key Laboratory of Dunhuang Medicine, Ministry of Education
Shenzhen Luohu District People 's Hospital