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Exploring Effect of Method of Warming Yang and Relieving Depression on Susceptibility to Mental Disorders in a Two-hit Mice via BDNF/TrkB Signaling Pathway
Exploring Effect of Method of Warming Yang and Relieving Depression on Susceptibility to Mental Disorders in a Two-hit Mice via BDNF/TrkB Signaling Pathway
- “The method of warming yang and relieving depression can improve anxiety and depressive like behavior in mice subjected to secondary attacks. Researchers have established a mother infant separation combined with restraint stress model, explored the BDNF/TrkB pathway, HPA axis, and 5-HT energy system mechanisms, and opened up new directions for traditional Chinese medicine research on the prevention and treatment of emotional disorders.”
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 19, Pages: 154-163(2026)
DOI: 10.13422/j.cnki.syfjx.20260340
Revised:2026-02-06 ,
Accepted:10 February 2026
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Related Author
YANG Haoruo
ZHANG Ningxin
JIN Qiubai
LI Jiaqi
XIAO Xue
SUN Meiqi
YANG Bin
SONG Ping
Related Institution
Tianjin University of Traditional Chinese Medicine
Xiyuan Hospital, China Academy of Chinese Medical Sciences
Beijing University of Chinese Medicine
School of Basic Medicine,Chengdu University of TCM
Zigong Hospital of TCM


