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Effect of Runmu Xiaoyao Powder on TLR4/MyD88/NF-κ B Signaling Pathway in Mice with Dry Eye and Liver Depression-heat Syndrome
Effect of Runmu Xiaoyao Powder on TLR4/MyD88/NF-
κ B Signaling Pathway in Mice with Dry Eye and Liver Depression-heat Syndrome- “Runmu Xiaoyao Powder may downregulate the activity of TLR4/MyD88/NF - κ B signaling pathway in the cornea, lacrimal gland, and meibomian gland of mice with dry eye liver meridian stagnation and heat syndrome, inhibit inflammatory response, and reduce ocular surface tissue damage. Researchers have established a mouse model of dry eye liver meridian stagnation and heat syndrome, explored the mechanism of action of Runmu Xiaoyao Powder, and provided a new solution for the treatment of dry eye with traditional Chinese medicine.”
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 13, Pages: 112-122(2026)
DOI: 10.13422/j.cnki.syfjx.20260366
Revised:2026-03-25 ,
Accepted:08 April 2026
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Related Author
XIE Jiajia
CHEN Sisi
WU Huiqin
LI Hang
XU Zheng
DENG Xi
XU Mingzhi
PENG Jun
Related Institution
Shenzhen Bao'an Traditional Chinese Medicine Hospital,Guangzhou University of Chinese Medicine
The Seventh Clinical Medical College,Guangzhou University of Chinese Medicine
The First Hospital of Hunan University of Chinese Medicine
Hunan Engineering Technology Research Center for the Prevention and Treatment of Otorhinolaryngologic Diseases and Protection of Visual Function with Chinese Medicine
Zhejiang Medical Health Group Quzhou Hospital Ophthalmology Center


