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Mechanism of Qifu Lizhong Decoction in Repairing Intestinal Mucosal Barrier and Improving Ulcerative Colitis via Myosin Light Chain Kinase （MLCK）/ Phosphorylated Myosin Light Chain （p-MLC） Signaling Pathway
Updated：2026-09-03
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    • Mechanism of Qifu Lizhong Decoction in Repairing Intestinal Mucosal Barrier and Improving Ulcerative Colitis via Myosin Light Chain Kinase （MLCK）/ Phosphorylated Myosin Light Chain （p-MLC） Signaling Pathway

    • “Qifu Lizhong Tang may improve UC by inhibiting the MLCK/p-MLC signaling pathway, stabilizing the TJ structure, and repairing the integrity of the intestinal barrier. The research team explored the mechanism by which this formula regulates the intestinal mucosal barrier, providing a new treatment option for ulcerative colitis.”
    • TANG Junmei , QU Zhengwu , LI Chunrun , YUAN Lingling , YANG Xuli , HAO Yanwei , ZHANG Yi
    • Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 19, Pages: 174-184(2026)

    • DOI： 10.13422/j.cnki.syfjx.20260439     

      CLC：

    • Revised：2026-02-27 ，

      Accepted：04 March 2026 ，

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