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Investigation of Mechanism of Simiaowan in Promoting Intestinal Uric Acid Excretion in Hyperuricemic Rats by Inhibiting Ferroptosis of Intestinal Epithelial Cells via SLC7A11/GPX4 Signaling Pathway
Updated：2026-09-07
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    • Investigation of Mechanism of Simiaowan in Promoting Intestinal Uric Acid Excretion in Hyperuricemic Rats by Inhibiting Ferroptosis of Intestinal Epithelial Cells via SLC7A11/GPX4 Signaling Pathway

    • “Simiao Pill inhibits ferroptosis of ileal epithelial cells and upregulates the expression of uric acid transporter ABCG2 by regulating the SLC7A11/GPX4 signaling pathway, thereby promoting intestinal uric acid excretion and improving HUA, providing a new solution for the treatment of hyperuricemia.”
    • ZHANG Zhongyou , FENG Huilin , DUAN Lian , FAN Xuping , DONG Shaoang , WANG Lingchun , YE Bowen , DAI Hao
    • Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 18, Pages: 151-161(2026)

    • DOI： 10.13422/j.cnki.syfjx.20260461     

      CLC：

    • Revised：2026-04-10 ，

      Accepted：20 April 2026 ，

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