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Modified Guizhi Fulingwan Regulates miR-34a-5p/DLL1/Notch Signaling Pathway to Promote Apoptosis and Inhibit Prostate Cancer
Updated：2026-09-07
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    • Modified Guizhi Fulingwan Regulates miR-34a-5p/DLL1/Notch Signaling Pathway to Promote Apoptosis and Inhibit Prostate Cancer

    • “Based on the traditional Chinese medicine theory of "yang transforming qi, yin shaping", researchers explored the molecular mechanism of Guizhi Fuling Wan modified formula in promoting cell apoptosis and anti prostate cancer. They found that it inhibits the DLL1/Notch signaling pathway by upregulating miR-34a-5p expression, providing experimental evidence for elucidating the anti prostate cancer mechanism of this compound.”
    • DONG Yuanguang , YANG Ying , SUN Penghao , HONG Yang , PAN Lu , LI Jiapeng , ZHOU Lijiang , ZHANG Di , YUAN Mingdian
    • Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 18, Pages: 122-133(2026)

    • DOI： 10.13422/j.cnki.syfjx.20260517     

      CLC：

    • Revised：2026-04-15 ，

      Accepted：19 April 2026 ，

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