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Mechanism of Chidamide Combined with Compound Kushen Injection on Breast Cancer Cells Based on Transcriptomics
Mechanism of Chidamide Combined with Compound Kushen Injection on Breast Cancer Cells Based on Transcriptomics
Enhanced Publication- “The combination of Sidabenamide and Compound Sophora flavescens injection can synergistically inhibit breast cancer MCF-7 cells. The "One Belt and One Line" method is used to screen the best synergetic concentration. Its mechanism involves HDAC1 inhibition and cAMP/PKA/CREB pathway activation, which opens up a new direction for the research of combined drugs for breast cancer.”
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 17, Pages: 134-143(2026)
DOI: 10.13422/j.cnki.syfjx.20260665
Revised:2026-05-09 ,
Accepted:02 June 2026
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Related Author
SUN Zibo
YAO Jing
PAN Tingyu
ZHAO Qi
WANG Jing
ZHAO Jun
XU Yong
ZHOU Xianmei
Related Institution
Affiliated Hospital of Nanjing University of Chinese Medicine
The First Clinical Medical College,Nanjing University of Chinese Medicine
School of Chinese Medicine,Nanjing University of Chinese Medicine
College of Traditional Chinese Medicine(TCM),Ningxia Medical University
Shaanxi University of Chinese Medicine


