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Hei Xiaoyaosan Ameliorates Cognitive Impairment in Rat Model of Alzheimer's Disease by Clearing Peripheral Aβ via AMPK/SREBP2/PCSK9/LRP-1 Signaling Pathway
Updated：2026-10-16
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    • Hei Xiaoyaosan Ameliorates Cognitive Impairment in Rat Model of Alzheimer's Disease by Clearing Peripheral Aβ via AMPK/SREBP2/PCSK9/LRP-1 Signaling Pathway

    • “Black Xiaoyao Powder regulates the AMPK/SREBP2/PCSK9/LRP-1 signaling pathway to clear peripheral A β and prevent cognitive impairment in Alzheimer's disease, providing a new solution for AD treatment.”
    • NIE Zifan , MA Yingchuan , PEI Wenli , HAN Yumei , YANG Jiao , JIN Ruixue , WANG Qian , WANG Huping
    • Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 22, Pages: 61-73(2026)

    • DOI： 10.13422/j.cnki.syfjx.20260740     

      CLC：

    • Revised：2026-04-23 ，

      Accepted：24 April 2026 ，

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Related Author

HAN Yumei
NIE Zifan
LYU Yujie
HU Yunyun
MENG Zhipeng
CHEN Yiqin
PEI Wenli
HAN Yumei

Related Institution

Research Center of TCM
Gansu Key Laboratory of Traditional Chinese Medicine Excavation and Innovative Transformation
Gansu Engineering Laboratory for New Products of Traditional Chinese Medicine
Gansu Key Laboratory of TCM Excavation and Innovative Transformation
Gansu Engineering Laboratory for New Products of Traditional Chinese Medicine （TCM）， Gansu Key Laboratory of TCM Excavation and Innovative Transformation，Gansu University of Chinese Medicine