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PK-PD Profiling of Active Components in Eucommia ulmoides Extract with Aortic Vascular Endothelial Cells from a SHR Model
PK-PD Profiling of Active Components in
Eucommia ulmoides Extract with Aortic Vascular Endothelial Cells from a SHR Model- “The research on the antihypertensive mechanism of Eucommia ulmoides has made progress, and researchers have constructed a pharmacokinetic pharmacodynamic (PK-PD) combined model of Eucommia ulmoides active ingredients to clarify the pharmacological substances directly related to the antihypertensive effect of Eucommia ulmoides. It has been found that increasing the release of NO in the body may be an important pathway for Eucommia ulmoides to exert its antihypertensive effect, providing new ideas for the research of traditional Chinese medicine pharmacological substances.”
- Chinese Journal of Experimental Traditional Medical Formulae Pages: 1-8(2026)
DOI： 10.13422/j.cnki.syfjx.20260902
Revised：2026-05-13 ，
Accepted：18 May 2026
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Related Author
JIN Yang
HU Hejie
CHEN Yi
PENG Jianqing
LI Yueting
ZHENG Lin
HUANG Yong
CHEN Siying
Related Institution
Guizhou Key Laboratory of Modern Traditional Chinese Medicine Creation
State Key Laboratory of Discovery and Utilization of Functional Components in Traditional Chinese Medicine， Engineering Research Center for the Development and Application of Ethnic Medicine and TCM （Ministry of Education）， School of Pharmacy， Guizhou Medical University
School of Life Sciences， Beijing University of Chinese Medicine
School of Pharmacy，Shanghai University of Traditional Chinese Medicine
School of Graduate Studies，Tianjin University of Traditional Chinese Medicine（TCM）
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