“Research has found that tumor associated bone marrow mesenchymal stem cells and multi nucleated myeloid derived suppressor cells can synergistically activate MIF/SDF-1/CXCR4 and MMP-9/α 4 β 1/CD106 axis through crosstalk, thereby significantly enhancing the invasion and migration ability of gastric cancer cells. The team established a co culture system of TA BMSCs and PMN MDSCs, explored the multi-target intervention mechanism of Banxia Xiexin Tang drug containing intestinal absorption solution, and opened up a new direction for the treatment of gastric cancer.”