Construction of Prescription Database of The Four Medical Tantras and Analysis of Its Medication Rules Based on Complex Network Analysis and Visual FoxPro
Data Mining|更新时间:2021-02-09
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Construction of Prescription Database of The Four Medical Tantras and Analysis of Its Medication Rules Based on Complex Network Analysis and Visual FoxPro
Chinese Journal of Experimental Traditional Medical FormulaeVol. 25, Issue 22, Pages: 175-185(2019)
Dang-zhi WENCHENG, Dong-zhi GONGBAO, Ren-qing DUOJI, et al. Construction of Prescription Database of The Four Medical Tantras and Analysis of Its Medication Rules Based on Complex Network Analysis and Visual FoxPro. [J]. Chinese Journal of Experimental Traditional Medical Formulae 25(22):175-185(2019)
DOI:
Dang-zhi WENCHENG, Dong-zhi GONGBAO, Ren-qing DUOJI, et al. Construction of Prescription Database of The Four Medical Tantras and Analysis of Its Medication Rules Based on Complex Network Analysis and Visual FoxPro. [J]. Chinese Journal of Experimental Traditional Medical Formulae 25(22):175-185(2019) DOI: 10.13422/j.cnki.syfjx.20191360.
Construction of Prescription Database of The Four Medical Tantras and Analysis of Its Medication Rules Based on Complex Network Analysis and Visual FoxPro
in which drug treatment is one of the four main treatment methods
and prescriptions are the main form of clinical drug use. The study on the medication rules of
The Four Medical Tantras
has positive significance for the clinical medication research of Tibetan medicine.
Method:
2
Prescriptions recorded in
Secret Medical Code
and
Follow
-
up Medical Code
from
The Four Medical Tantras
were collected
the prescription database was constructed by Visual FoxPro 9.0
combined the dual perspectives of the " fifteen categories" (skabs bco lnga) of Tibetan medical diseases and the " eighteen practices" (lag len bco brgyad) of treatment
and Gephi 0.9.2 complex network was used to analyze its medication rules.
Result:
2
The Four Medical Tantras
contained 2 695 Tibetan medicine prescriptions
average number of drugs in each prescription was 6.6
prescription composed of ≤7 drugs accounted for 69.2%of the total prescription. There were 1 002 kinds of medicines involved in the total prescription
of which 156 was the nodal degrees of Chebulae Fructus
Bambusae Concretio Silicea
Carthami Flos
Piperis Longi Fructus and Zingiberis Rhizoma and so on; followed by 91 nodal degrees of butter (mar)
sugar
barley sweetener (sbang ma)
honey and brown sugar and so on
which were Tibetan medicinal and edible medicines. According to the classification of diseases in the fifteen categories
there were 495 prescriptions for traumatology (mtshon rma)
323 for fever (tsha ba)
278 for toxics and 197 for three factors diseases. According to the treatment method of eighteen practices
162 powder
77 decoction
84 laxative (bxhal) and others were used. Association rule analysis found that edge weights of Borneolum Syntheticum
Bambusae Concretio Silicea
Carthami Flos
Santali Albi Lignum and other cold medicines were 59
edge weights of pomegranate seeds
Piperis Longi Fructus
Cinnamomi Cortex
Amomi Fructus Rotundus and other warm medicines were 45.
Conclusion:
2
The Four Medical Tantras
has some characteristics
including the medication rules of elliptic philosophy with cool-warm medicinal properties as the dual core
elimination-diarrhea (zhi-sbyong) as medication methods
weight of rlung-mkhris pa-bad kan as medication dialectical thinking and so on. Among them
the clinical application of butter
barley sweetener
sugar and other special delivery agents of Tibetan medicine is prominent. The prominent clinical application of special Tibetan medicines embodies the philosophy of Tibetan culture with the emphasis on overall balance. It has the multi-dimensional medication rule of " diet plus medicine
medicine plus therapy"
and has positive significance for revealing the research on medication rules of Tibetan medicine.
关键词
《四部医典》藏族药方剂数据库用药规律复杂网络十五会十八实践
Keywords
The Four Medical TantrasTibetan medicineprescriptiondatabasemedication rulecomplex networkfifteen categorieseighteen practices
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Related Author
WANG Huanhuan
CHANG Mengli
LI Yu
ZHANG Fengrong
XU He
ZHANG Yi
TANG Shihuan
PAN Mingmin
Related Institution
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences
Hospital of Integrated Chinese and Western Medicine, Tianjin University of Traditional Chinese Medical
Institute of Basic Theroy for Chinese Medicine,China Academy of Chinese Medical Sciences
Henan University of Chinese Medicine
Shandong University of Traditional Chinese Medicine