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Xuefu Zhuyutang Treats Coronary Heart Disease with Blood Stasis Syndrome in Rats via SIRT3 Signaling Pathway-mediated Regulation of Endothelial Function
Updated:2026-07-16
    • Xuefu Zhuyutang Treats Coronary Heart Disease with Blood Stasis Syndrome in Rats via SIRT3 Signaling Pathway-mediated Regulation of Endothelial Function

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    • “Xuefu Zhuyu Tang may activate the SIRT3 signaling pathway, synergistically regulate the expression of key proteins such as HIF-1 α, PFKFB3, PPAR γ, β - catenin, etc., and regulate endothelial function from multiple aspects such as metabolic homeostasis, cell connectivity stability, and vascular coordination, thereby promoting the repair and functional improvement of myocardium in rats with coronary heart disease and blood stasis syndrome. Researchers have explored the mechanism of traditional Chinese medicine compound intervention in coronary heart disease and blood stasis syndrome, opening up a new direction for the integrated treatment of cardiovascular diseases with traditional Chinese and Western medicine.”
    • YAN Qing , YU Yonghong , TIAN Peng , SU Chang , LIANG Hao , YANG Yang , PENG Qinghua , ZHANG Qiuyan
    • Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 16, Pages: 28-37(2026)
    • DOI: 10.13422/j.cnki.syfjx.20252242     

      CLC:
    • Revised:2025-11-12 ,

      Accepted:17 November 2025 ,

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LIU Yi
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SU Chang
TIAN Peng
WANG Mingyun
ZHONG Ruqian
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Related Institution

Provincial Key Laboratory of Traditional Chinese Medicine(TCM) Diagnostics, Hunan University of Chinese Medicine
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Hunan Provincial Key Laboratory of Traditional Chinese Medicine Diagnostics,College of Chinese Medicine,Hunan University of Chinese Medicine
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