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Xuefu Zhuyutang Treats Coronary Heart Disease with Blood Stasis Syndrome in Rats via SIRT3 Signaling Pathway-mediated Regulation of Endothelial Function
Xuefu Zhuyutang Treats Coronary Heart Disease with Blood Stasis Syndrome in Rats via SIRT3 Signaling Pathway-mediated Regulation of Endothelial Function
Enhanced Publication- “Xuefu Zhuyu Tang may activate the SIRT3 signaling pathway, synergistically regulate the expression of key proteins such as HIF-1 α, PFKFB3, PPAR γ, β - catenin, etc., and regulate endothelial function from multiple aspects such as metabolic homeostasis, cell connectivity stability, and vascular coordination, thereby promoting the repair and functional improvement of myocardium in rats with coronary heart disease and blood stasis syndrome. Researchers have explored the mechanism of traditional Chinese medicine compound intervention in coronary heart disease and blood stasis syndrome, opening up a new direction for the integrated treatment of cardiovascular diseases with traditional Chinese and Western medicine.”
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 16, Pages: 28-37(2026)
DOI: 10.13422/j.cnki.syfjx.20252242
Revised:2025-11-12 ,
Accepted:17 November 2025
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Related Author
LIU Yi
YANG Yang
SU Chang
TIAN Peng
WANG Mingyun
ZHONG Ruqian
XIE Xuejiao
YAN Qing
Related Institution
Provincial Key Laboratory of Traditional Chinese Medicine(TCM) Diagnostics, Hunan University of Chinese Medicine
Hunan Traditional Chinese Medical College
Hunan Provincial Key Laboratory of Traditional Chinese Medicine Diagnostics,College of Chinese Medicine,Hunan University of Chinese Medicine
Guang'anmen Hospital, China Academy of Chinese Medical Sciences
The Second Clinical Medical College, Heilongjiang University of Chinese Medicine


