“Banxia Xiexin Tang was first published in "Treatise on Cold Damage" and "Synopsis of the Golden Chamber". It introduces the research progress of Banxia Xiexin Tang in the field of multi system diseases based on the principles of "relieving bitterness and reducing stagnation, harmonizing the middle, and regulating cold and heat". The research team has established an evidence chain of "syndrome biomarker organ function clinical endpoint", which has opened up a new direction for the modernization of traditional Chinese medicine research.”