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Xuming Tongmai Decoction Regulates Autophagy and Apoptosis in Brain Tissue of Stroke Rats Through mTOR/HIF-1α /VEGF Signaling Pathway
Xuming Tongmai Decoction Regulates Autophagy and Apoptosis in Brain Tissue of Stroke Rats Through mTOR/HIF-1
α /VEGF Signaling Pathway- “Xuming Tongmai Tang can regulate the mTOR/HIF-1 α/VEGF signaling pathway, promote angiogenesis, inhibit neuronal autophagy and apoptosis, thereby improving neurological function in stroke rats and exerting neuroprotective effects. The research team introduced its research progress in the field of stroke treatment and explored the protective mechanism of traditional Chinese medicine compound on brain tissue damage, opening up new directions for the development of neuroprotective drugs.”
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 16, Pages: 107-116(2026)
DOI: 10.13422/j.cnki.syfjx.20260507
Revised:2026-03-23 ,
Accepted:25 March 2026
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Related Author
RAN Li
LAN Xiaofang
TANG Jun
YAN Keqiu
ZHANG Xiaoyu
SUN Guangjun
LIN Aizhen
DAI Ting
Related Institution
The First Affiliated Hospital of Chongqing University of Chinese Medicine, Chongqing Traditional Chinese Medicine Hospital
Hubei University of Chinese Medicine
Hubei Provincial Hospital of Traditional Chinese Medicine
Affiliated Hospital of Hubei University of Chinese Medicine
Hubei Provincial Institute of Traditional Chinese Medicine


