“The "inflammation cancer transformation" of digestive system tumors is a key factor in global cancer prevention and treatment. The Banxia Xiexin Tang formula effectively intervenes in precancerous lesions with the methods of "relieving bitterness, regulating cold and heat, and tonifying deficiency and diarrhea". This study systematically reviews its theoretical basis, clinical evidence, and multi-target mechanism of action, and constructs a "different disease treatment" research framework of "regulating the stable state of inflammatory microenvironment", providing a new direction for the precise prevention and control of digestive system tumors in traditional Chinese medicine.”