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Protective Effect of Kummerowia striata Extract Against Carbon Tetrachloride-induced Acute Liver Injury in Mice Based on Gut Microbiota-Nrf2/NF-κB/MAPK Axis
Updated:2026-07-16
    • Protective Effect of Kummerowia striata Extract Against Carbon Tetrachloride-induced Acute Liver Injury in Mice Based on Gut Microbiota-Nrf2/NF-κB/MAPK Axis

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    • “Chicken eye grass extract has a significant protective effect on acute liver injury induced by carbon tetrachloride in mice. Its mechanism may be related to activating the Nrf2/HO-1 signaling pathway to reduce oxidative damage, regulating the NF - κ B/MAPK signaling pathway to inhibit inflammatory response, and improving gut microbiota imbalance through the gut liver axis. This provides a new solution for the prevention and treatment of drug-induced liver injury.”
    • WANG Longguang , YIN Zhenhua , CUI Xuejing , MENG Yaxin , WANG Ruyi , NING Zhao , LIU Yihua , CHEN Lin
    • Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 16, Pages: 179-188(2026)
    • DOI: 10.13422/j.cnki.syfjx.20260614     

      CLC:
    • Revised:2026-04-28 ,

      Accepted:06 May 2026 ,

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