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Protective Effect of Kummerowia striata Extract Against Carbon Tetrachloride-induced Acute Liver Injury in Mice Based on Gut Microbiota-Nrf2/NF-κ B/MAPK Axis
Protective Effect of
Enhanced PublicationKummerowia striata Extract Against Carbon Tetrachloride-induced Acute Liver Injury in Mice Based on Gut Microbiota-Nrf2/NF-κ B/MAPK Axis- “Chicken eye grass extract has a significant protective effect on acute liver injury induced by carbon tetrachloride in mice. Its mechanism may be related to activating the Nrf2/HO-1 signaling pathway to reduce oxidative damage, regulating the NF - κ B/MAPK signaling pathway to inhibit inflammatory response, and improving gut microbiota imbalance through the gut liver axis. This provides a new solution for the prevention and treatment of drug-induced liver injury.”
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 16, Pages: 179-188(2026)
DOI: 10.13422/j.cnki.syfjx.20260614
Revised:2026-04-28 ,
Accepted:06 May 2026
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Related Author
LI Qijing
HUANG Hanhui
DENG Yurong
WANG Ao'ao
LI Jianliang
SUN Jianhui
HAO Liyu
LI Zongyuan
Related Institution
National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences
Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences
Tianjin University of Traditional Chinese Medicine
State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs,China Academy of Chinese Medical Sciences
First Clinical Medical College, Shandong University of Traditional Chinese Medicine(TCM)


