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Mechanism of Kaixuan Jiedu Core Prescription in Ameliorating Psoriasis-like Inflammation via TrkA Receptor-mediated Regulation of CGRP Expression and Dendritic Cell Activation
Updated:2026-09-03
    • Mechanism of Kaixuan Jiedu Core Prescription in Ameliorating Psoriasis-like Inflammation via TrkA Receptor-mediated Regulation of CGRP Expression and Dendritic Cell Activation

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    • “The Kaixuan Detoxification Core Formula can target the inhibition of TrkA receptor phosphorylation, regulate the expression of CGRP in skin lesions, improve abnormal activation of dendritic cells, thereby alleviating mouse psoriasis like inflammation induced by imiquimod and significantly inhibiting keratinocyte proliferation, providing a new approach for the treatment of neuroimmune inflammation in psoriasis.”
    • LIU Huan , JIANG Mengyao , LI Jiaqi , SUN Meiqi , XIAO Xue , ZHANG Ningxin , YANG Bin , SONG Ping
    • Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 19, Pages: 102-110(2026)
    • DOI: 10.13422/j.cnki.syfjx.20260642     

      CLC:
    • Revised:2026-04-05 ,

      Accepted:07 April 2026 ,

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Related Author

LIU Huan
LI Jiaqi
SUN Meiqi
XIAO Xue
ZHANG Ningxin
YANG Bin
SONG Ping
XIAO Xue

Related Institution

Xiyuan Hospital of China Academy of Chinese Medical Sciences
Tianjin University of Traditional Chinese Medicine
Graduate School, China Academy of Chinese Medical Sciences
Beijing University of Chinese Medicine
Shaanxi University of Chinese Medicine