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Hei Xiaoyaosan Ameliorates Cognitive Impairment in Rat Model of Alzheimer's Disease by Activating Autophagy Through Regulating AMPK/ULK1 Signaling Pathway
Updated：2026-10-16
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    • Hei Xiaoyaosan Ameliorates Cognitive Impairment in Rat Model of Alzheimer's Disease by Activating Autophagy Through Regulating AMPK/ULK1 Signaling Pathway

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    • “Black Xiaoyao Powder can improve the learning and memory abilities and pathological status of AD model rats, and its mechanism may be related to regulating the AMPK/ULK1 signaling pathway, enhancing cellular autophagy, and repairing damaged nerve cells. The research team has verified a new mechanism of traditional Chinese medicine compound for preventing and treating Alzheimer's disease, opening up new directions for the study of traditional Chinese medicine intervention in neurodegenerative diseases.”
    • PEI Wenli , HAN Yumei , NIE Zifan , MA Yingchuan , JIN Ruixue , WANG Qian , YANG Jiao , WANG Huping
    • Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 22, Pages: 91-101(2026)

    • DOI： 10.13422/j.cnki.syfjx.20260909     

      CLC：

    • Revised：2026-06-01 ，

      Accepted：03 June 2026 ，

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Related Author

HAN Yumei
PEI Wenli
NIE Zifan
MA Yingchuan
YANG Jiao
NIE Zifan
HAN Yumei
JIN Ruixue

Related Institution

Research Center of TCM
Gansu Key Laboratory of Traditional Chinese Medicine Excavation and Innovative Transformation
Gansu Engineering Laboratory for New Products of Traditional Chinese Medicine
Gansu Key Laboratory of TCM Excavation and Innovative Transformation
Gansu Engineering Laboratory for New Products of Traditional Chinese Medicine （TCM）， Gansu Key Laboratory of TCM Excavation and Innovative Transformation，Gansu University of Chinese Medicine