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Construction of Mouse Models of Psoriasis-like Lesions Induced by Cold Exposure Combined with Imiquimod and Evaluation of Therapeutic Efficacy of Kaixuan Jiedu Core Prescription
Construction of Mouse Models of Psoriasis-like Lesions Induced by Cold Exposure Combined with Imiquimod and Evaluation of Therapeutic Efficacy of Kaixuan Jiedu Core Prescription
- “The research team established a psoriasis like mouse model induced by continuous cold and intermittent cold combined with IMQ, and verified that the Kaixuan Jiedu Core Formula alleviates psoriasis like skin lesions under cold conditions by opening the Xuanfu, regulating vascular relaxation, and correcting immune inflammatory responses, opening up a new direction for the prevention and treatment of silver chip disease caused by cold pathogens.”
- Chinese Journal of Experimental Traditional Medical Formulae Vol. 32, Issue 19, Pages: 69-78(2026)
DOI: 10.13422/j.cnki.syfjx.20261126
Revised:2026-03-28 ,
Accepted:08 April 2026
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Related Author
LIU Huan
JIANG Mengyao
LI Jiaqi
SUN Meiqi
XIAO Xue
ZHANG Ningxin
XIAO Xue
YANG Bin
Related Institution
Tianjin University of Traditional Chinese Medicine
Xiyuan Hospital of China Academy of Chinese Medical Sciences
Shaanxi University of Chinese Medicine
Shaanxi Provincial Hospital of Chinese Medicine
Xi'an No.9 Hospital


