Li Zongduo, Dong Yuxiu, Li Wenquan, et al. Pharmacological Activities of the“Guanlida Capsule”[J]. Chinese journal of experimental traditional medical formulae, 1996, 2(5): 22-26.
Li Zongduo, Dong Yuxiu, Li Wenquan, et al. Pharmacological Activities of the“Guanlida Capsule”[J]. Chinese journal of experimental traditional medical formulae, 1996, 2(5): 22-26.DOI:
The results of this study revealed that the administration of the capsule showed the following pharmacological functions in experimental aninials:reducing acute myocardlal infarction size (MJS) of rats by nitroblue tetrazolium technique and the change of ST section and T wave in electrocardiograph (ECG) by i.v. injection of 0.5 U/kg of hypophysine
raising the tolerance of mice to hypoxia
abating the release of creatine phosphokinase (cpk) from the myocardial ischaemia tissue in rats
increasing 86Rb intake of the heart and the myocardial nutritional blood flow in mice. In twenty-four open-chest anesthetized dogs
the capsule expanded coronary arteries
increased the coronary volume of blood flow
and decreased the total peripheral vascular resistance(TPVR).