Feng Guoqing1, Fu Runfang1, Wu Hongxia1, et al. Studies on Antibacterial and Antistomatocace Effectsand Toxicology of Zhenzhu Koutaiyaomo[J]. Chinese journal of experimental traditional medical formulae, 1998, 4(1): 28-30.
Feng Guoqing1, Fu Runfang1, Wu Hongxia1, et al. Studies on Antibacterial and Antistomatocace Effectsand Toxicology of Zhenzhu Koutaiyaomo[J]. Chinese journal of experimental traditional medical formulae, 1998, 4(1): 28-30.DOI:
Zhenzhu Koutaiyaomo can markedly shorten the healing time of oralmucosa ulcer induced by electric burn in guinea pig and relieve its symptoms.It could sligntly inhibit the α-hemolytic streptococcus.The toxicology study showed that Zhenzhu Koutaiyaomo had no distinct toxicity
stimulation and allergy with smearing on the oral membrane and skin of guinea pig.The maximal tolerance dose of mice is 4 g·kg-1·d-1(ig) which is 7272.73 times as much as it is in the clinical dosage.It demonstrated that Zhenzhu Koutaiyaomo had no toxicity and was used safely in clinic.