龟芪散及其拆方对免疫抑制小鼠IL-2产生及其基因转录的影响

朱晓新1; 吴敦序2; 王露3

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龟芪散及其拆方对免疫抑制小鼠IL-2产生及其基因转录的影响

更新时间：2024-01-04

- 龟芪散及其拆方对免疫抑制小鼠IL-2产生及其基因转录的影响
- Effects of Guiqi Powder and Its Simplified Formula on IL-2 mRNA and Protein Expression Level of Immunosuppressed Mice
- 中国实验方剂学杂志 1998年4卷第5期页码：15-18
- 作者机构：
- 作者简介：
- 基金信息：
  
  上海市教委资助项目
- DOI：
  中图分类号： R-332;R285.5
- 纸质出版日期：1998
- 稿件说明：
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朱晓新1, 吴敦序2, 王露3. 龟芪散及其拆方对免疫抑制小鼠IL-2产生及其基因转录的影响[J]. 中国实验方剂学杂志, 1998,4(5):15-18.

Zhu Xiaoxin1, Wu Dunxu2, Wang Lu3. Effects of Guiqi Powder and Its Simplified Formula on IL-2 mRNA and Protein Expression Level of Immunosuppressed Mice[J]. Chinese journal of experimental traditional medical formulae, 1998, 4(5): 15-18.
朱晓新1, 吴敦序2, 王露3. 龟芪散及其拆方对免疫抑制小鼠IL-2产生及其基因转录的影响[J]. 中国实验方剂学杂志, 1998,4(5):15-18. DOI：

Zhu Xiaoxin1, Wu Dunxu2, Wang Lu3. Effects of Guiqi Powder and Its Simplified Formula on IL-2 mRNA and Protein Expression Level of Immunosuppressed Mice[J]. Chinese journal of experimental traditional medical formulae, 1998, 4(5): 15-18. DOI：

摘要

龟芪散及其拆方可明显增强Cy所致免疫受损小鼠T淋巴细胞的增殖;提高L3T+4细胞数量及L3T+4/Lyt+2细胞比率;促进脾细胞IL-2mRNA转录和IL-2产生。以全方效果最佳

亦好于PSP。但对正常小鼠无明显影响。

Abstract

Guiqi powder as a whole and its simplified formulae could promote significantly the proliferation of T lymphocytes

increase L3T+4 cells counts raise ratio of L3T+4/Lyt+2 cells and enhance spleen cells IL-2 mRNA and protein expression level in immunosuppressed mice caused by cyclophosphamide.The original Guiqi powder as a whole was more potent than its simplified formula as well as PSP.However it showed no effects in normal mice.

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