Lu Shu, Yang Di, Weng Xiaosheng, et al. Effect of Jiangfang Baoxin Decoction on Renin Angiotensin System in Renovascular Hypertensive Rats[J]. Chinese journal of experimental traditional medical formulae, 1999, 5(3): 26-30.
Lu Shu, Yang Di, Weng Xiaosheng, et al. Effect of Jiangfang Baoxin Decoction on Renin Angiotensin System in Renovascular Hypertensive Rats[J]. Chinese journal of experimental traditional medical formulae, 1999, 5(3): 26-30.DOI:
The study has investigated the effects of Jiangfang Baoxin decoction (JF) on blood pressure(BP)
left ventricular hypertrophy(LVH)
and renin angiotensin system(RAS) of circulation and left ventricule in renovascular hypertensive rats(RHR).The results indicated that JF can reduce BP of RHR
and decrease the enhanced left ventricular wet weight to body weight ratio of RHR.The level of angiotensin Ⅱ(AngⅡ)was decreased significantly in left ventricule of RHR treated with JF for 10 weeks.Angiotensin converting enzyme(ACE) activity was also reduced in lung.The trend of ACE was decreased in left ventricule and serum