Objective: To compare the cellular immune function of Liaoning

Jilin and Korean ginseng in immunosuppressed mice. Method: Immunosuppressed model of mouse was induced by subcutaneous injection of hydrocortisone. Three decoctions of ginseng originated from Liaoning

Jilin and Korea were ig given to explore CD3

CD4

CD8 in spleen cell suspension by flow cytometry. Serum IFN-γ level was determined by ELISA assay;and SRBC was used to induce delayed-type hypersensitivity (DTH). Result: The CD3

CD4 and CD8 of spleen cell suspension were increased after each ginseng decoction treatment

Korean ginseng could increase the CD4 and CD4/CD8 ratio for the immunosuppressed mice significantly(P<0.05). Liaoning ginseng had no significant difference compared with that of Jilin ginseng or Korean ginseng. The levels of DTH and IFN-γwere also raised significantly after each decoction treatment(P<0.05)

and Liaoning ginseng had no significant difference compared with that of Jilin ginseng or Korean ginseng. Conclusion: Liaoning ginseng decoction can improve cellular immune function on immunosuppressed mice

and Liaoning ginseng had no significant difference compared with Jilin and Korean ginseng.