Bioavailability was important evaluation index of safety and effectiveness of drugs.Consult data library such as Wan Fang

CNKI

OVI and so on

comprehensive analyzed and reviewed more than 150 related data recent 10 years from domestic and abroad. Summarized the influencing factors of bioavailability from two aspects of medicine and biology

consist of the form of drugs

physicochemical property

the preparation technology

physiological environment of gastrointestinal

the delivery time and way and so on. Some new research ideas like the pro-drug strategy

the gastro-retentive drug delivery system

cyclodextrin closure technology

solid dispersion technique

co-grinding technology

nano-technology etc. for improving bioavailability of traditional chinese medicine (TCM)preparations were discussed in order to provide reference for the research on modernization of TCM preparations.