Objective: To investigate the curative effect of Guizhi Fuling capsules (GFC) supplemented to western medicine for treating ectopic pregnancy. Method: Eighty cases of ectopic pregnancy patients were randomly divided into the observation group and the control group

40 cases in each group.Mifepristone was used in control group

25 mg orally bid for 3 days; and methotrexate (MTX) 50 mg·m-2

deep intramuscular injection on both sides of the buttocks

once daily.On the basis of the control group

the observation group were received GFC 9 capsules bid for 4 weeks.Serum β-HCG level and mass changes were monitored

the β-HCG returned to normal and mass disappearance time required were recorded. Result: The conservative success rate (90%

35 cases) in the observation group was better than that (72.5%

29 patients) in control group (P<0.05).The average recovery time of serum β-HCG 35 of observation group was (14.5±7.7)d

less than that in control group (18.4±8.5)d (P<0.05).The mass narrowing of 32 cases in observation group in 3 weeks was better than that (21 cases) in control group.The clinical symptoms disappeared in 34 cases in observation group within 2 weeks was superior than 23 cases in control group (P<0.05). Conclusion: GFC combined with methotrexate and mifepristone improves the success rate of conservative treatment of ectopic pregnancy

and safe for clinical use.