Objective:To optimize extraction technology of liposoluble and water soluble ingredients from Salvia miltiorrhiza. Method: With the content of tanshinone ⅡA as index

effect of ethanol concentration

the amount of ethanol

extraction time and frequency on extraction technology of liposoluble ingredients from S. miltiorrhiza by single factor test and orthogonal test;With the content of salvianolic acid B as index

influence of water amount

extraction time and times on water-soluble ingredients from S. miltiorrhiza by L9(34) orthogonal test. Result: Optimal extraction technology of liposoluble ingredients was as following:extracted 3 times with 8 times the amount of 70% ethanol

30 min each time;Optimum extraction technology of water-soluble constituents from S. miltiorrhiza was as following:extracted 3 times with 5 times the amount of water

30 min each time. Conclusion: This optimized extraction technology was simple

stable and feasible

it was suitable for industrial production with a good prospect.