Objective: To optimize molding formula of Xiaoshi granules. Method: Taking relative density of extraction solution

accessories multiples and proportion of mixed subsidiary materials as investigating factors

with composite score of qualified granules ratio and solubility as index

molding formula of Xiaoshi granules was optimized by L9(34) orthogonal test. Result: The best molding formula was that the relative density of extraction solution of 1.30(60 ℃)

the amount of subsidiary material of 2.5 times

dextrin-starch of 1:1. Conclusion: This optimized molding formula of Xiaoshi granules was reasonable

stable and reliable

it could be extended to large-scale production application.