抗流感口服液的提取工艺优选

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抗流感口服液的提取工艺优选

更新时间：2024-01-04

- 抗流感口服液的提取工艺优选
- Optimization of Extraction Process of Kangliugan Oral Liquid
- 中国实验方剂学杂志 2013年19卷第4期页码：31-34
- 作者机构：
- 作者简介：
- 基金信息：
  
  南昌市科技支撑计划(2010KJZCJH-YYYYLQX-065)
- DOI：
  中图分类号：
- 纸质出版日期：2013
- 稿件说明：
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饶小勇, 何双凤, 吴志鹏, 等. 抗流感口服液的提取工艺优选[J]. 中国实验方剂学杂志, 2013,19(4):31-34.

RAO Xiao-yong, HE Shuang-feng, WU Zhi-peng, et al. Optimization of Extraction Process of Kangliugan Oral Liquid[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(4): 31-34.
饶小勇, 何双凤, 吴志鹏, 等. 抗流感口服液的提取工艺优选[J]. 中国实验方剂学杂志, 2013,19(4):31-34. DOI：

RAO Xiao-yong, HE Shuang-feng, WU Zhi-peng, et al. Optimization of Extraction Process of Kangliugan Oral Liquid[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(4): 31-34. DOI：

目的: 优选抗流感口服液的提取工艺。方法: 以解热药效为指标

采用药效跟踪试验考察提取溶媒和提取方式;以黄芩苷转移率为指标

采用正交试验法考察提取时间、提取次数及溶剂用量对抗流感口服液提取工艺的影响。结果: 最佳提取工艺为加12倍量水提取3次

每次1 h

黄芩苷转移率85.41%。结论: 采用药效跟踪试验可保障产品的有效性

优选的提取工艺稳定、可行、操作性强。

Objective: To optimize extraction technology of Kangliugan oral liquid. Method: With antipyretic efficacy as index

extraction solvent and method were investigated by pharmacodynamic tracking test;With transfer rate of baicalin as index

extraction process of Kangliugan oral liquid was optimized by orthogonal experiment with solvent amount

extraction time and times as factors. Result: Optimum extraction process was as following:extracted 3 times with 12 times the amount of water

1 h each time

transfer rate of baicalin was 85.41%. Conclusion: Pharmacodynamic tracking test could guarantee effectiveness of products

this optimized extraction technology was stable

feasible and workable.

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