Objective: To explore ultrafiltration technology of total saponin from Panax notoginseng injection. Method: Contents of ginsenoside Rg1

Rb1 and notoginsenoside R1 were determined by HPLC

effect of different factors on ultrafiltration technology were investigated by single factor test

including different molecular weight ultrafiltration membrane

the concentration and temperature of solution

lotion volume. Relust: 10 kDa ultrafiltration membrane was chosen

determined ultrafiltration technology was:the mass concentration of water solution of 100 g· L-1

ultrafiltration temperature 70℃

lotion volume 1 200 mL

transmission of ginsenoside Rg1

Rb1 and notoginsenoside R1 were more than 90%. Conclusion: This optimized ultrafjltration technology was feasible for purification of total saponin of P. notoginseng.