LI Hai-yan, SONG Han-min, LI Zhen-guo. Studies of Quality Standard on Peiyuantongnao Capsule[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(2): 129-132.
LI Hai-yan, SONG Han-min, LI Zhen-guo. Studies of Quality Standard on Peiyuantongnao Capsule[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(2): 129-132.DOI:
4'-四羟基二苯乙烯-2-O-β-D葡萄糖苷的含量。色谱条件:Agilent ZORBAX SB-C18色谱柱(4.6 mm×250 mm
5 μm)
流动相乙腈-水(15:85)
流速 1.0 mL·min-1。 结果: TLC的斑点清晰、分离度较好
阴性无干扰;2
3
5
4'-四羟基二苯乙烯-2-O-β-D葡萄糖苷在0.064 5~0.805 9 μg线性关系良好
平均回收率为99.4%
RSD 2.2%(n=6)。 结论: 所建标准可用于培元通脑胶囊的质量控制。
Abstract
Objective: To establish the methods of identification and assay in Peiyuantongnao Capsule. Method: TLC was used to determine Polygonum multiflorum
Cinnamomum cassia
Paeoniae radix rubra
Herba Cistanches and HPLC was used to determine the content of stilbene glycoside. Result: The spots of TLC were fairly clear with the good separation. The linear range of baicalin was from 0.064 5 to 0.805 9 μg. The average recovery was 99.4%
RSD was 2.2% (n=6). Conclusion: The established standard is applicable for the quality control of Peiyuantongnao Capsule.