Objective: To study the effects of Morindae Officinalis Radix (RMO) on the exercise capacity and mitochondrial antioxidant capacity of rats. Method: The high-intensity endurance training was used to establish model. Fifty-five Wistar rats were divided into 5 groups (n=10 for group):motionless group (C group)

exercise group (T group)

exercise ig low-dose RMO group of (RMOL group)

exercise ig middle-dose of RMO group (RMOM group)

exercise ig high-dose of RMO group (RMOH group). The dose was 4

8

12 g·kg-1·d-1

ig volume 5 mL·kg-1

administration lasted 6 weeks. At 24 h after the last training

weight

exhaustive swimming time

the various indicators of fatigue-related content were measured in mitochondria

such as malondialdehyde (MDA)

etc.Result: Weight of each RMO group was greater than the T group (P<0.05)

swimming time was longer than T group (P<0.01). Exhaustive swimming increased the MDA conten in T group and RMO groups(6.06±0.24)

(5.07±0.56)

(5.08±0.79)

(5.09±0.53) μmol·L-1

and that the RMO groups was significantly lower than the T group (P <0.01). superoxide dismutace(SOD)

glutathi one peroxidace(GSH-Px) activity was significantly decreased [T-group and RMO groups

SOD decreased to(211.35±20.37)

(255.85±10.31)

(258.98±8.24)

(263.31±12.69)U·mL-1

GSH-Px decreased to(55.72±14.23)

(70.64±5.83)

(70.96±4.96)

(71.38±5.06)U·mg-1]

and the RMO group was significantly higher than the T group (P<0.01).Conclusion: RMO has the effects on improving the exercise capacity and the mitochondrial antioxidant enzyme activity.