Objective: To observe the main effects of the Qinxian capsule in the treatment on asthma

cough

phlegm and anti-inflammatory. Method: Fifty rats were divided into 5 groups

the normal group

Qinxian capsules high (4.59 g·kg-1)

middle(2.30 g·kg-1)

low (1.15 g·kg-1)

Aminophylline (50 mg·kg-1)

by Ovalbumin induced asthma for the determination of the incubation period of asthma;50 mice divided into 5 group

the normal group Qinxian capsules high (6.63 g·kg-1)

middle (3.32 g·kg-1)

low (1.66 g·kg-1) dose group

Fu fang Gancao tablets group (0.14 g·kg-1) or ammonium chloride (0.12 g·kg-1)

with ammonia water spray determination of cough incubation period and 3 min cough frequency

determining phenolsulfonphthalein excretion quantity;50 mice were divided into 5 groups

the normal group

Qinxian capsules high (6.63 g·kg-1)

middle (3.32 g·kg-1)

low (1.66 g·kg-1) dose group

Dexamethasone group (2 mg·kg-1)

using xylene induced ear swelling and determining the swelling degree

using Granuloma hyperplasia model for determination of granulation quality

comprehensive study on the main pharmacodynamics of capsule in treating bronchial asthma. Result: Qinxian capsules high

low dose group of rats with asthma latency was significantly prolonged (P<0.05)

high

low dose group of mice cough frequency was significantly reduced and latency was significantly prolonged (P<0.01

P<0.05)

high

middle dose group mouse tracheal phenol red excretion increased significantly (P<0.05)

auricle swelling degree significantly reduced (P<0.01

P<0.05)

high

low dose group mice agar granuloma growth was significantly reduced (P<0.01). Conclusion: Qinxian capsules has reducing cough and resolving phlegm and anti-inflammatory effects

on bronchial asthma with therapeutic effect.