Objective:To explore the effects of Xuebijing injection on blood gas analysis and cardiac function in patients with acute exacerbation of chronic pulmonary and heart disease. Method: Seventy-six cases with acute exacerbation of chronic pulmonary and heart disease were randomly divided into control group and treatment group. Each group contained 38 cases. Patients in control group were received with conventional therapy

while the cases in treatment group were given with conventional therapy plus Xuebijing injection for iv infusion (50 mL

bid) for four weeks. Result: The levels of PaO2

PaCO2

hemorheological parameters

mean pulmonary artery pressure and cardiac output were obviously improved

compared with those of control group after the treatment (P<0.05). The effective rate of treatment group was 86.84%

which was higher than that of control group (60.53%

P<0.05). Conclusion: Treatment with Xuebijing injection could improve the blood gas analysis and cardiac function in patients with acute exacerbation of chronic pulmonary and heart disease.