Objective: To explore the effect of Xiaoqinglong decoction on the airway inflammation and the cytokine production in asthmatic mice. Method: Thirty BALB/c mice were randomly divided into normal control group (group A)

asthmatic model group (group B)

Xiaoqinglong decoction treatment group (C group). B

C

ovalbumin was injected intraperitoneally and aerosol inhalation to stimulate the production of the asthma model. From 21 to 28 days

group A

group B were given normal saline 15 mL ·kg-1 orally

group C was given Xiaoqinglong decocotion 15 g ·kg-1 1 h before stimulating. Bronchoalveolar lavage fluid(BALF) was collected to count the number of total number of inflammatory cells and esinophil and determine BALF supernatant interleukin-4(IL-4) and interferon-γ(IFN-γ) levels. Result: Xiaoqinglong decocotion intervention could significantly reduce the total number of inflammatory cells and Eosnumber

the supernatant of IFN-γ levels were significantly elevated

IL-4 levels were significantly decreased.There was a significant difference among group C and group A

B(P<0.05). Conclusion: Xiaoqinglong decocotion can significantly reduce the number of inflammatory cells in BALF of asthmatic mice and impact the levels of cytokines

thereby improving airway inflammation in asthma.