Objective: To observe anti-inflammatory and analgesic effects of ethanol extracts of Dong-medicine Inual cappa. Method: Mice divided into blank control group

low dose group and high dose group (2.5

5 g·kg-1) of ethanol extracts of I. cappa DC. and positive control group of aspirin (0.25 g·kg-1). The anti-inflammatory action was assessed by tests including HAc-induced peritoneal capillary permeability in mice

xylene-induced ear edema in mice.The analgesic effect was verified by HAc-induced writhing response in mice and hot-plate test. Result: The dose group of the ethanol extracts of I. cappa DC. (5 g·kg-1)could significantly inhibit the ear edema induced by xylene (P<0.05)and very significantly inhibit the phlogistic infiltration induced by acetic acid in mice(P<0.01).The dose group of the ethanol extracts of Inual cappa DC. (5 g·kg-1)could significantly reduced writhes of abdominal cavity induced by acetic acid in 20 minutes and increased the pain threshold in the hot-plate test(P<0.01

P<0.01). Conclusion: Ethanol extracts of Inual cappa DC. have obvious anti-inflammatory and analgesic effects.