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纸质出版日期:2013
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石绍顺, 于雪峰, 李丁蕾, 等. 清肺平喘颗粒联合固本清肺贴膏治疗支气管哮喘(热哮证)[J]. 中国实验方剂学杂志, 2013,19(3):269-271.
SHI Shao-shun, YU Xue-feng, LI Ding-lei, et al. Qingfei Pingchuan Grain with Guben Qingfei Plaster Treat Active Asthma(Thermal Asthma Syndrome)[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(3): 269-271.
石绍顺, 于雪峰, 李丁蕾, 等. 清肺平喘颗粒联合固本清肺贴膏治疗支气管哮喘(热哮证)[J]. 中国实验方剂学杂志, 2013,19(3):269-271. DOI:
SHI Shao-shun, YU Xue-feng, LI Ding-lei, et al. Qingfei Pingchuan Grain with Guben Qingfei Plaster Treat Active Asthma(Thermal Asthma Syndrome)[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(3): 269-271. DOI:
目的: 观察内服(清肺平喘颗粒)联合外敷(固本清肺贴膏)治疗支气管哮喘发作期的疗效和安全性。方法: 将120例支气管哮喘发作期(热哮证)患者随机分为试验组和对照组
分别接受清肺平喘颗粒联合固本清肺贴膏(简称试验组)与茶碱缓释片(0.2 g
2次/d)联合布地奈德粉吸入剂(100 μg
2次/d)(简称对照组)治疗
观察治疗前后临床疗效、中医症状积分、肺功能[1秒钟用力呼气量(FEV1)
最大呼气流量(PEF)变异率]、哮喘控制测试(ACT)积分等指标。结果: 疾病疗效为试验组显效率为78.18%
总有效率为92.73%
对照组显效率为80.39%
总有效率为90.20%
两组间无明显差异;中医症候疗效:试验组显效率为63.63%
总有效率为92.73%
对照组显效率为52.94%
总有效率为88.24%
两组间无明显差异;两组对肺功能及哮喘控制测试积分的改善无明显差异;试验过程中未发现心、肝、肾及血液系统的损害
不良反应少。结论: 内服(清肺平喘颗粒)联合外敷(固本清肺贴膏)治疗支气管哮喘发作期(热哮证)安全可靠
疗效确切。
Objective: To obsreve the effects and security of oral(Qingfei Pingchuan grain)with sticking(Guben Qingfei plaster)treating active asthma. Method: One hundred and twenty patients with hermal asthma syndrome were randomized to two groups.the control group treated with theophylline and budesonide powder for inhalation
experimental group treated with Qingfei Pingchuan grain and Guben Qingfei plaster. Before and after treatment
clinical efficacy
TCM symptom score
lung function forced expiratory rolume in one second (FEV1)
peak expictory flow(PEF) mutation rate
asthma control test(ACT)integral Etc were observed. Result: In experimental group
markedly effective rate was 78.18%
total effective rate was 92.73%;in the control group
markedly effective rate was 80.39%
total effective rate was 90.20%
there was no significant difference between the two groups. In terms of TCM symptom score
in experimental group:markedly effective rate was 63.63%
total effective rate was 92.73%; in the control group markedly effective rate was 52.94%
the total effective rate was 88.24%
there was no significant difference between the two groups. There was no significant difference between the two groups in lung function and ACT integral. Conclusion: Oral administration of Qingfei Pingchuan grain combined with externaluse of Guben Qingfei plaster in treating active asthma (thermal asthma syndrome)is safe and effective.
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