LI Min-zhou, GAO Yan-bin, MA Ming-fei, et al. Overview of Current Researches on Pathogenetic Mechanisms of Diabetic Nephropathy[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(22): 344-349.
LI Min-zhou, GAO Yan-bin, MA Ming-fei, et al. Overview of Current Researches on Pathogenetic Mechanisms of Diabetic Nephropathy[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(22): 344-349.DOI:
Diabetic nephropathies(DN) is the most common chronic complications of diabetes mellitus(DM)
and is the leading cause of end-stage renal disease(ESRD) either.There are a lot of pathogentic mechanisms can contribute to the development of the diaease
such as sugar metabolism disorders
hemodynamic dysfunctions
lipid metabolism disorders
cytokines
oxidatives stress mechanisms and genetic susceptibility etc.These pathogentic mechanisms will be overviewed as follows.