Objective: Explore the effects of Danhong injection on protect myocardium of acute coronary syndrome(ACS) patients after selective percutaneous coronary artery intervention(PCI). Method: Using a prospective design of experiments

the 68 patients of the intended line of PCI with ACS were randomly divided into treatment group and control group

each group is 34 patients. At the same time into the hospital health examination in 40 cases as health group.Observation the level of all patients of plasma endothelin-1(ET-1)

P-selectin (CD62p)

high enzyme C reactive protein (hs-CRP) and after treatment of 7 d ST segment resolution rate at PCI preoperatively

immediately after operation

treatment of 14 d. Using SPSS 9.0 statistical software for data statistics and analysis. Result: ACS patients preoperative plasma levels of ET-1

CD62p

hs-CRP were higher than the healthy group

The differences were statistically significant(P＜0.05). The treatment group compared with the control group

the difference was not statistically significant 14 days after treatment

two groups of patients with ET-1

CD62p

hs-CRP levels were decreased compared with those before treatment

the difference was statistically significant(P<0.05); The treatment group compared with the control group

treatment group

ET-1

CD62p

hs-CRP were lower than the control group

the difference was statistically significant(P<0.05). After treatment of 7 d

the treatment group ST segment resolution higher than that in the control group

the difference was statistically significant (P<0.05). Conclusion: Danhong injection can inhibit ASC in patients with PCI postoperative inflammatory reaction

protection of endothelial cells

is proposed as PCI postoperative myocardial protection measures in clinical treatment